The compound, called AEF0117, is a signaling inhibitor, which means it blocks only “a pocket” of the CB1 receptor, explains Margaret Haney, PhD, director of the Cannabis Research Laboratory.
“For individuals with ADHD a simple task can seem very daunting and requires a lengthy thought process,” said Jacques Ambrose, MD, assistant professor of psychiatry.
“This is one of the very few medications that I’ve tested to directly decrease the effects of cannabis,” Margaret (Meg) Haney, PhD, the director of the cannabis research laboratory at Columbia, said.
In a Phase 2a clinical trial, Columbia researchers found that the drug AEFO117 significantly reduced the effects of cannabis in daily cannabis smokers.
Dr. Nathan Ha specializes in providing mental health care to adults and older adolescents and has expertise in helping those affected by differences of race, ethnicity, gender, and sexuality.
“She was the first person I saw as a patient,” said Sander Markx, MD, who was a medical student in 2000 when he first encountered April. “She is, to this day, the sickest patient I’ve ever seen.”
“Our nervous system is wired to act and help us to remain safe from harm. This often assists us to help meet goals and aspirations but sometimes causes anxiety,” says Anne Marie Albano, PhD.
The concept of losing face or bringing shame to family and community, a fear that’s universal across many Asian cultures, can heavily affect Asian Americans’ decision to get help, said Warren Ng, MD.
Zachary Blumkin, PsyD, addresses some of the pitfalls of social media and offer suggestions for how teens (and their parents) can engage with social media safely.
Casey O’Brien, PsyD, discusses the recently launched Columbia Intensive Adolescent and Family DBT Program, which teaches teens specific, tangible skills toward acceptance and changing behaviors.