Columbia University Medical Center
NewYork-Presbyterian Hospital The University Hospital of Columbia and Cornell


    Contact Us

  • Columbia University Pediatric & Mood Research Clinic
  • (Tel) (646)-774-5793
  • 1051 Riverside Dr New York, NY 10032


OCD Treatment & Research Program

Principal Investigator: Moira Rynn, M.D.

Click HERE for more information about our OCD Treatment & Research Program

Meet one of our OCD experts, Dr. Anthony Puliafico, to learn more about his work at our program:

What is Obsessive-Compulsive Disorder (OCD)?

We all have habits and routines; however, people with OCD have habits and routines that get in the way of their daily lives. If your child's fay to day life is affected by these symptoms, OCD may be the cause.

The symptoms of OCD include:

  • Repeated and unwanted ideas, impulses or thoughts that cause nervousness or fear (Obsessions)
  • Performing repetitive behaviors to get rid of the uncomfortable fear or thoughts (Compulsions)


Does your child have OCD?
Is he/she taking medication and still struggling with OCD?

doctor with parent discussing OCD

The Columbia University Pediatric Anxiety and Mood Research Clinic specializes in treating children and teens that have tried front-line treatments like medication or therapy but continue to struggle with OCD. We are currently investigating a new medication treatment for children, adolescents, and young adults with OCD.

By participating in our OCD treatment and research program, your child will receive a thorough evaluation and may be eligible to receive treatment at no cost to you.


Research Program Overview

This research study aims to determine whether adding an FDA-approved antibiotic medication called minocycline to SRI treatment can help reduce symptoms of OCD. This study also aims to learn more about the brains of children and adolescents with OCD.

There are two main phases in our program. Phase 1 lasts for 12 weeks and consists of the following:

  • screening period of 1-2 visits to determine if your child is eligible, including a free, thorough psychiatric evaluation.
  • 12 weeks of medication treatment with minocycline or *placebo (pills with no medication in them) at no cost.
  • 7 visits with the study doctor; one hour visit at the start followed by 30 minute visits every two weeks.
  • 2 brain scans in a magnetic resonance imaging (MRI) machine.

*2/3 participants receive minocycline in phase 1.

In phase 2, participants receive medication management and/or cognitive-behavioral therapy (CBT) for three months at no cost. This includes:

  • Minocycline offered to participants who received placebo in phase 1.
  • OCD-specific CBT treatment by experts, including Exposure & Response Prevention (ERP) therapy if appropriate.
  • Additional medication care by psychiatrists specializing in OCD treatment.

Study testing, medication and evaluations will be provided at no cost to you. In addition, you and your child will receive compensation to cover travel expenses, and other related incidentals.


Who is eligible to participate?

Your child may be eligible to participate in this program if he/she is diagnosed with Obsessive-Compulsive Disorder.

Additionally, your child must:

  • Be between 8 and 20 years of age.
  • Currently be taking a serotonin reuptake inhibitor (SRI). Examples of SRI medication include Prozac, Zoloft, Luvox, Paxil, Lexapro, Celexa, and Anafranil.
  • Not be pregnant, nursing or planning to become pregnant in the next year.


Interested in learning more about this research program?

We are happy to answer any questions you may have!

Please contact:

Dylan Braun
Phone: 646-774-5793


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