Brain Imaging Lab

The Brain Imaging Lab is housed in the Molecular Imaging and Neuropathology Area at the New York State Psychiatric Institute and the Department of Psychiatry at Columbia University Irvine Medical Center. The lab conducts studies that increase our understanding of the neurobiology of mood disorders and suicide and the mechanisms of medication and psychotherapeutic interventions with a goal to develop more effective treatments. The lab also focuses on the development and application of a wide range of computational tools and statistical methods to address these topics using multimodal neuroimaging (functional, structural, and molecular in vivo neuroimaging) and genomics data in healthy humans and patients with mood disorders.

Lab Members

Directors

  • Jeffrey Miller, MD

    • Associate Professor of Clinical Psychiatry
  • Francesca Zanderigo, PhD

    • Associate Professor of Clinical Neurobiology (in Psychiatry)

Principal Investigators and Faculty

  • Todd Ogden, PhD

    • Professor, Biostatistics (in Psychiatry)
  • Spiro P. Pantazatos, PhD

    • Assistant Professor of Clinical Neurobiology (in Psychiatry)
  • Dongrong Xu, PhD

    • Associate Professor of Clinical Neurobiology (in Psychiatry)
  • Zhengchao Dong, PhD

    • Associate Professor of Clinical Neurobiology (in Psychiatry)
  • M. Elizabeth Sublette, MD, PhD

    • Professor of Clinical Psychiatry
  • Martin J. Lan, MD, PhD

    • Assistant Professor of Psychiatry
  • Noam Schneck, PhD

    • Assistant Professor of Clinical Medical Psychology (in Psychiatry)
  • Elizabeth Bartlett, PhD

    • Assistant Professor of Clinical Neurobiology (in Psychiatry)

Fellows and Assistant Research Scientists

  • Mike Schmidt, PhD

    • Postdoctoral Research Scientist
  • Christina A. Michel, PhD

    • Paul Janssen Fellow in Translational Neuroscience Research
  • Gjertrud Louise Laurell, PhD

    • Postdoctoral Researcher
  • Granville J. Matheson, PhD

    • Postdoctoral Researcher

Select Publications

  • Dynamic human brain imaging with the portable Positron Emission Tomography camera CerePET: comparison to a standard scanner Bartlett EA, Lesanpezeshki M, Anishchenko S, Shkolnik I, Ogden RT, Mann JJ, Beylin D, Miller JM, Zanderigo F Journal of Nuclear Medicine 2023; (in press)

  • In vivo serotonin transporter and 1A receptor binding potential and ecological momentary assessment (EMA) of stress in major depression and suicide Bartlett EA, Zanderigo F, Stanley B, Choo TH, Galfalvy HC, Pantazatos SP, Sublette ME, Miller JM, Oquendo MA, Mann JJ European Neuropsychopharmacology 2023; 70: 1-13

  • Ventral prefrontal serotonin 1A receptor binding: a neural marker of vulnerability for mood disorder and suicidal behavior? Pantazatos SP, Melhem N, Brent DA, Zanderigo F, Bartlett E, Lesanpezeshki M, Burke A, Miller JM, Mann JJ Molecular Psychiatry 2022; 27(10): 4136-4143

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