Muhammad O. Chohan, MD

  • Assistant Professor of Clinical Psychiatry
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Overview

Muhammad O. Chohan, MD, is an Assistant Professor of Clinical Psychiatry within the Division of Child and Adolescent Psychiatry at the Columbia University Irving Medical Center (CUIMC) and the New York State Psychiatric Institute (NYSPI).

Dr. Chohan obtained his medical degree in Pakistan. During medical school, he completed an internship at CUIMC and NYSPI where he examined the relationship between interneuron dysfunction and psychosis. After graduating from medical school, he did postdoctoral work on dopamine and glutamate abnormalities in psychosis and obsessive-compulsive disorder at CUIMC and NYSPI. Dr. Chohan hopes to draw on his clinical background and research training to develop new approaches to understanding and treating the cognitive, motivational, and motor abnormalities that are characteristic of neuropsychiatric disorders.

Academic Appointments

  • Assistant Professor of Clinical Psychiatry

Gender

  • Male

Research

Selected Publications

Developmental impact of glutamate transporter overexpression on dopaminergic neuron activity and stereotypic behavior. Mol Psychiatry. 2022 Jan 20;. doi: 10.1038/s41380-021-01424-3. [Epub ahead of print] PubMed PMID: 35058566.

Accumbens dopamine D2 receptors increase motivation by decreasing inhibitory transmission to the ventral pallidum. Nat Commun. 2018 Mar 14;9(1):1086. doi: 10.1038/s41467-018-03272-2. PubMed PMID: 29540712; PubMed Central PMCID: PMC5852096.

OCD candidate gene SLC1A1/EAAT3 impacts basal ganglia-mediated activity and stereotypic behavior. Proc Natl Acad Sci U S A. 2017 May 30;114(22):5719-5724. doi: 10.1073/pnas.1701736114. Epub 2017 May 15. PubMed PMID: 28507136; PubMed Central PMCID: PMC5465902.

Interneuron precursor transplants in adult hippocampus reverse psychosis-relevant features in a mouse model of hippocampal disinhibition. Proc Natl Acad Sci U S A. 2014 May 20;111(20):7450-5. doi: 10.1073/pnas.1316488111. Epub 2014 May 2. PubMed PMID: 24794528; PubMed Central PMCID: PMC4034251.

Dopamine D2 receptors regulate the anatomical and functional balance of basal ganglia circuitry. Neuron. 2014 Jan 8;81(1):153-64. doi: 10.1016/j.neuron.2013.10.041. PubMed PMID: 24411738; PubMed Central PMCID: PMC3899717.

For a complete list of publications, please visit PubMed.gov