J John Mann, MD
On the web
Overview
J John Mann MD, is The Paul Janssen Professor of Translational Neuroscience (in Psychiatry and in Radiology) and a former Vice Chair for Research in the Department of Psychiatry at Columbia University. He is Director of Research and Director of Molecular Imaging and the Neuropathology Division at the New York State Psychiatric Institute.
Dr. Mann is trained in Psychiatry and Internal Medicine and has a Doctorate in Neurochemistry. His research employs functional brain imaging, neurochemistry and molecular genetics to probe the causes of depression and suicide. Dr. Mann is the Director of the NIMH Conte Center for the Neuroscience of Mental Disorders, and Past President of the International Academy of Suicide Research.
Dr. Mann has published 458 papers and edited 10 books on the subjects of the biology and treatment of mood disorders, suicidal behavior and other psychiatric disorders. In private practice he specializes in the treatment of mood disorders.
Areas of Expertise / Conditions Treated
- Adjustment Disorder
- Anxiety Disorders
- Attention Deficit Hyperactivity Disorder (ADHD)
- Bipolar Disorder
- Depression
- Generalized Anxiety Disorder
- General Psychiatry
- Insomnia
- Mental Health
- Mood Disorders
- Obsessive Compulsive Disorder (OCD)
- Panic Disorder
- Psychopharmacology
- Psychosis
- Psychotherapy
- Social Anxiety Disorder
Academic Appointments
- Paul Janssen Professor of Translational Neuroscience (in Psychiatry and in Radiology)
Hospital Affiliations
- NewYork-Presbyterian / Columbia University Irving Medical Center
Gender
- Male
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Location(s)
Credentials & Experience
Education & Training
- MD, University of Melbourne, Faculty of Medicine (Australia)
- Residency: Royal Melbourne Hospital
Board Certifications
- Psychiatry
Research
Clinical Trials
Selected Publications
- Coombes BJ, Sanchez-Ruiz JA, Fennessy B, Pazdernik VK, Adekkanattu P, Nuñez NA, Lepow L, Melhuish Beaupre LM, Ryu E, Talati A, Mann JJ, Weissman MM, Olfson M, Pathak J, Charney AW, Biernacka JM. Clinical associations with treatment resistance in depression: An electronic health record study. Psychiatry Res. 2024 Dec;342:116203. doi: 10.1016/j.psychres.2024.116203. Epub 2024 Sep 16. PMID: 39321638; PMCID: PMC11617277.
- Patra BG, Lepow LA, Kasi Reddy Jagadeesh Kumar P, Vekaria V, Sharma MM, Adekkanattu P, Fennessy B, Hynes G, Landi I, Sanchez-Ruiz JA, Ryu E, Biernacka JM, Nadkarni GN, Talati A, Weissman M, Olfson M, Mann JJ, Zhang Y, Charney AW, Pathak J. Extracting social support and social isolation information from clinical psychiatry notes: comparing a rule-based natural language processing system and a large language model. J Am Med Inform Assoc. 2025 Jan 1;32(1):218-226. doi: 10.1093/jamia/ocae260. PMID: 39423850; PMCID: PMC11648716.
- Herzog S, Bartlett EA, Zanderigo F, Galfalvy HC, Burke A, Mintz A, Schmidt M, Hauser E, Huang YY, Melhem N, Sublette ME, Miller JM, Mann JJ. Neuroinflammation, Stress-Related Suicidal Ideation, and Negative Mood in Depression. JAMA Psychiatry. 2025 Jan 1;82(1):85-93. doi: 10.1001/jamapsychiatry.2024.3543. PMID: 39504032; PMCID: PMC11541744.
- Wickramaratne PJ, Yangchen T, Lepow L, Patra BG, Glicksberg BS, Talati A, Adekkanattu P, Ryu E, Biernacka JM, Charney A, Mann JJ, Pathak J, Olfson M, Weissman MM. Correction: Social connectedness as a determinant of mental health: A scoping review. PLoS One. 2024 Nov 15;19(11):e0314220. doi: 10.1371/journal.pone.0314220. Erratum for: PLoS One. 2022 Oct 13;17(10):e0275004. doi: 10.1371/journal.pone.0275004. PMID: 39546492; PMCID: PMC11567508.
- Chen Y, Chauhan S, Gong C, Dayton H, Xu C, De La Cruz ED, Tsai YW, Datta MS, Rosoklija GB, Dwork AJ, Mann JJ, Boldrini M, Leong KW, Dietrich LEP, Tomer R. Low-cost and scalable projected light-sheet microscopy for the high-resolution imaging of cleared tissue and living samples. Nat Biomed Eng. 2024 Sep;8(9):1109-1123. doi: 10.1038/s41551-024-01249-9. Epub 2024 Aug 29. PMID: 39209948.
For a complete list of publications, please visit PubMed.gov