Adrian Jacques Ambrose, MD, MPH, FAPA, medical director of the Columbia Psychiatry Faculty Practice Organization, discusses the newest research into the neuroscience of anxiety and depression.
“Ketamine is a medical treatment intended to address a significant illness,” such as severe depression or suicidal ideation, said Joshua Berman, assistant professor of psychiatry at Columbia.
"Many patients report rapid improvement in mood, anxiety and hedonic function, which is what initially attracted the psychiatric profession to the use of ketamine," said Dr. Joshua Berman.
Ketamine, a compound initially used as an anesthetic, holds exciting promise as a newer alternative to more traditional treatment approaches for depression.
Dr. Michael Grunebaum thinks the drug should no longer be relegated to a last-line treatment. “It makes sense that it move up in the treatment algorithm in E.R.s and inpatient units,” he said.
Ketamine was significantly more effective than a commonly used sedative in reducing suicidal thoughts in depressed patients, according to researchers at Columbia University Medical Center (CUMC).